An automated confocal microscope available for high throughput imaging.

Objectives: 5x air, 10x air, 20x air, 20x water (NA1.1), 40x water (NA1.1) 63x water (NA1.2)

Lasers: 325, 425, 488, 560, 640

Image analysis software: Columbus Image Analysis Server website available via a VPN, for 3D analysis Harmony Image Analysis via remote desktop to PC via a VPN

From the Perkin Elmer website:

Speed or Sensitivity – No Compromise

Proprietary Synchrony^™ Optics combine a microlens enhanced Nipkow spinning disk with dual view confocal optics to separate fluorescence excitation and emission during simultaneous acquisition minimizing spectral crosstalk – for greater speed and higher sensitivity.

• Up to four large format sCMOS cameras with simultaneous acquisition in up to four channels, so you can generate images of exceptional quality – faster than ever
• Custom-designed high NA water immersion objectives to capture more photons and provide high image resolution even in thick samples
• State-of-the-art sCMOS image sensors deliver low signal-to-background noise, a wide dynamic range and high resolution – ideal for sensitive and quantitative measurements at short exposure times
• Spinning microlens disk with increased pinhole-to-pinhole distance to further reduce out-of-focus noise in thick samples such as microtissues
• Spinning disk optics and precise synchronization of the excitation laser and camera to minimize phototoxicity and bleaching for live cell assays
• Widefield or confocal imaging modes depending on your assay requirements
• Fast laser-based autofocus to ensure sharp confocal images from every field
• Modular design to adapt the system to your changing application needs – choose from single, dual or four camera configuration with four solid state lasers or a five laser system optimized for FRET applications